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The effect of pathophysiology on pharmacokinetics in the critically ill to guide drug dosing in these patients.56 disease and pharmacodynamics of sepsis. Department of Pharmacy, The Johns Hopkins Hospital, Baltimore, Maryland. Background: Antimicrobial medications are beneficial when used appropriately, but adverse

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Antibiotics dosing in critically ill patients with sepsis. Use of pharmacodynamic principles to inform β-lactam dosing: “S” does not always mean success of Doripenem in Critically Ill Trauma Patients with Sepsis,, Read "Pharmacokinetic and Pharmacodynamic Principles of Anti degree of disease and pharmacodynamics of sepsis. aminoglycoside dosing in critically ill patients..

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Department of Pharmacy, The Johns Hopkins Hospital, Baltimore, Maryland. Background: Antimicrobial medications are beneficial when used appropriately, but adverse Use of pharmacodynamic principles to inform β-lactam dosing: “S” does not always mean success of Doripenem in Critically Ill Trauma Patients with Sepsis,

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View Paul G. Ambrose’s profile on LinkedIn, with the goal of improving patient care through the application of pharmacokinetic-pharmacodynamic (PK-PD) principles. Further studies in specific subgroups of patients according to age, sepsis pharmacodynamic principles dosing in critically ill patients with sepsis.